February 17, 2004Circulation
Predictors of Outcome After Alcohol Septal Ablation Therapy in Patients With Hypertrophic Obstructive Cardiomyopathy
Why the study?
What are the independent predictors of an unsatisfactory outcome after alcohol septal ablation in patients with hypertrophic obstructive cardiomyopathy?
Population
173 consecutive patients with hypertrophic obstructive cardiomyopathy
Design
Cohort
Authors
Discussion
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Member takes
Implication
May flag higher-risk ASA patients intra-procedurally; hypothesis-generating and should not yet change practice.
Structured PICO
What are the independent predictors of an unsatisfactory outcome after alcohol septal ablation in patients with hypertrophic obstructive cardiomyopathy?
P
Population
173 consecutive patients with hypertrophic obstructive cardiomyopathy
I
Intervention
Alcohol septal ablation (ASA)
O
Outcome
Unsatisfactory outcome, defined as unchanged symptoms with <50% reduction of baseline left ventricular outflow tract (LVOT) gradientcomposite
Residual LVOT gradient ≥25 mm Hg in the catheterization laboratory and peak CK leak <1300 U/L are independent predictors of an unsatisfactory outcome after alcohol septal ablation for hypertrophic obstructive cardiomyopathy.
Cite This Study
Chang et al. (2004) studied this question.