Why the study?
Is mean platelet volume increased in patients after myocardial infarction compared to age-matched controls?
Population
100 patients soon after myocardial infarction and age-matched controls
Design
Cohort
Follow-up
about seven weeks
Authors
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Elevated post-MI mean platelet volume may signal altered platelet reactivity; hypothesis-generating for thrombotic risk and requires prospective validation before clinical use.
Is mean platelet volume increased in patients after myocardial infarction compared to age-matched controls?
Increased mean platelet volume after myocardial infarction suggests that abnormal platelet behavior, specifically larger and more hemostatically active platelets, may be implicated in the infarction process.
Cameron et al. (1983) studied this question.
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