Key result
Acute myocardial infarction was associated with a large mean platelet volume and low count, present in over 60% of MI patients compared with 13% of ischaemic heart disease controls.
Why the study?
Is acute myocardial infarction associated with differences in mean platelet volume and platelet count compared to myocardial ischemia or asymptomatic controls?
Population
Patients with acute myocardial infarction, a control group with myocardial ischaemia but no infarction, and…
Design
Case-control
Authors
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May aid MI identification; hypothesis-generating for prognosis and therapy pending validation.
Case-Control
Is acute myocardial infarction associated with differences in mean platelet volume and platelet count compared to myocardial ischemia or asymptomatic controls?
Absolute Event Rate: 60% vs 13%
Large mean platelet volume and low platelet count are associated with acute myocardial infarction and may represent a major risk factor.
Kishk et al. (1985) conducted a case-control in Acute myocardial infarction. Acute myocardial infarction vs. Myocardial ischaemia without infarction was evaluated on High platelet volume and low count. Acute myocardial infarction was associated with a large mean platelet volume and low count, present in over 60% of MI patients compared with 13% of ischaemic heart disease controls.
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