Key result
A tailored anticoagulation regimen using multiple laboratory tests (anti-Xa, aPTT, ACT, viscoelastic tests, AT, platelets, fibrinogen, FXIII) is proposed for ECMO patients.
Why the study?
High-quality data to personalize anticoagulation management in ECMO are lacking, resulting in high practice variability among centers.
Design
Literature review and pragmatic protocol proposal
Authors
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Single assays should not solely guide ECMO anticoagulation now; leaves open prospective trials of multimodal pragmatic protocols.
A tailored anticoagulation regimen using a comprehensive array of laboratory tests is recommended for patients on V-V ECMO due to the lack of a single predictive test for bleeding or thrombosis.
Rodrigues et al. (2024) conducted a review in V-V ECMO. Tailored anticoagulation management and monitoring was evaluated. A tailored anticoagulation regimen using multiple laboratory tests (anti-Xa, aPTT, ACT, viscoelastic tests, AT, platelets, fibrinogen, FXIII) is proposed for ECMO patients.
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