Why the study?
Does mechanical ventilation modulate left ventricular function by direct ventricular interaction in normal dogs?
Population
13 anesthetized, closed-chest, normal dogs
Comparison
Mechanical ventilation and maneuvers altering… vs Apnea / baseline states
Design
Preclinical
Authors
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May explain LV volume shifts during ventilation in normals; leaves open translation to clinical mechanical ventilation practice.
Does mechanical ventilation modulate left ventricular function by direct ventricular interaction in normal dogs?
Phasic changes in systemic venous return during mechanical ventilation modulate left ventricular function through direct ventricular interaction.
Mitchell et al. (2005) studied this question.
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