Balloon pulmonary angioplasty serves as a promising interventional treatment option for patients with inoperable chronic thromboembolic pulmonary hypertension, though procedure-related lung injury remains a significant challenge.
May offer symptomatic relief in select inoperable CTEPH; leaves open need for randomized trials to refine safety.
In chronic thromboembolic pulmonary hypertension (CTEPH), stenoses or obstructions of the pulmonary arteries due to organized thrombi can cause an elevation in pulmonary artery resistance, which in turn can result in pulmonary hypertension. CTEPH can be cured surgically by pulmonary endarterectomy (PEA); however, patients deemed unsuitable for PEA due to lesion, advanced age, or comorbidities have a poor prognosis and limited treatment options. Recently, advances have been made in balloon pulmonary angioplasty for these patients, and this review highlights this recent progress.
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Ogawa et al. (2015) studied this question.
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