Why the study?
Does surgical and chemical renal denervation reduce ventricular arrhythmia in a beagle model of myocardial infarction?
Population
24 beagles, including a myocardial infarction model established by permanent left anterior descending artery…
Comparison
Surgical and chemical renal denervation vs Sham procedure
Design
Preclinical, Randomized into control, renal denervation, and sham groups
Authors
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Should not alter clinical practice for post-MI arrhythmia; leaves open human translation of sympathetic modulation benefits.
Does surgical and chemical renal denervation reduce ventricular arrhythmia in a beagle model of myocardial infarction?
Surgical and chemical renal denervation reduces ventricular arrhythmia after myocardial infarction in a canine model by inhibiting sympathetic activity and reversing neural remodeling.
Zhang et al. (2018) studied this question.
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