Key result
Illicit drug use history in acute MI shows no significant link to higher one-year mortality.
Why the study?
Illicit drug use may be a major cause of AMI and associated with poorer prognosis, but its frequency and impact on short- and mid-term prognosis required determination.
Does a history of illicit drug use increase mortality in patients with acute myocardial infarction?
Observational (n=797,212)
Yes
Does a history of illicit drug use increase mortality in patients with acute myocardial infarction?
Odds Ratio: 1.12 (95% CI 0.98–1.29)
A history of illicit drug use, particularly opioids, is associated with increased one-year mortality in patients presenting with acute myocardial infarction despite a younger age at presentation.
No takes yet. Share an insight, caveat, or question.
Do not assume worse AMI outcomes from illicit-drug history alone; leaves open independent effects given administrative-data limits.
Genet et al. (2020) conducted an observational in Acute myocardial infarction (AMI) (n=797,212). History of illicit drug use (cannabis, cocaine or opioid) vs. No history of illicit drug use was evaluated on Death at one year (OR 1.12, 95% CI 0.98-1.29). A history of illicit drug use among patients with acute myocardial infarction was associated with a non-significant higher risk of death at one year (OR 1.12; 95% CI 0.98-1.29).
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