Cardio-oncology: what you need to know now for clinical practice and echocardiography

Figures

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  Figure 1. Global longitudinal strain before (A), during (B) and after (C) chemotherapy with trastuzumab.

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  Figure 2. Outline of a proposed model for risk assessment, monitoring and management of patients undergoing chemotherapy. ACE-I, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; CAD, coronary artery disease; cTn, cardiac troponin; ECG, electrocardiogram; HTN, hypertension; PAD, peripheral arterial disease; TTE, transthoracic echocardiogram. Reprinted from Mayo Clinic Proceedings, Volume 89(9), Joerg Herrmann, MD, Amir Lerman, MD, Nicole P. Sandhu, MD, PhD, Hector R. Villarraga, MD, Sharon L. Mulvagh, MD, and Manish Kohli MD, 2014, pages 1287–1306, with permission from Elsevier.

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  Figure 3. Algorithm for cardiac monitoring in patients receiving anthracyclines. ECHO, transthoracic echocardiogram; CTh, chemotherapy; Tnl, troponin; POS, positive; NEG, negative; LVD, left ventricular dysfunction; ACE, angiotensin-converting enzyme inhibitor; BB, beta blocker. Reprinted from: G. Curigliano, D. Cardinale, T. Suter, G. Plataniotis, E. de Azambuja, M.T. Sandri, C. Criscitiello, A. Goldhirsch, C. Cipolla & F. Roila, Cardiovascular toxicity induced by chemotherapy, targeted agents and radiotherapy: ESMO Clinical Practice Guidelines, Annals of Oncology, 2012, Volume 23 (supplement 7), pages vii155–vii166, by permission of Oxford University Press.

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  Figure 4. Algorithm for cardiac monitoring in patients receiving trastuzumab. LVEF, left ventricular ejection fraction. Reprinted from: G. Curigliano, D. Cardinale, T. Suter, G. Plataniotis, E. de Azambuja, M.T. Sandri, C. Criscitiello, A. Goldhirsch, C. Cipolla & F. Roila, Cardiovascular toxicity induced by chemotherapy, targeted agents and radiotherapy: ESMO Clinical Practice Guidelines, Annals of Oncology, 2012, Volume 23 (supplement 7), pages vii155–Vii166, by permission of Oxford University Press.