Why the study?
Does indobufen inhibit platelet aggregation in human subjects?
Population
12 subjects receiving oral doses and 5 subjects receiving intravenous doses
Comparison
Indobufen single oral doses of 100 mg and 300… vs Baseline and dose comparison
Design
Other
Follow-up
Acute (single dose)
Authors
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May support reversible antiplatelet strategies; leaves open comparative efficacy versus irreversible agents like aspirin.
Does indobufen inhibit platelet aggregation in human subjects?
Indobufen causes dose-dependent, reversible inhibition of platelet aggregation, distinguishing its mechanism from the irreversible effect of acetylsalicylic acid.
Vinazzer et al. (1980) studied this question.
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