What question did this study set out to answer?

To evaluate the efficacy and safety of prophylactic anticoagulation with warfarin in preventing venous thrombosis and pulmonary embolism in elderly patients with hip fractures.

July 21, 1966New England Journal of Medicine

Anticoagulation for Prevention of Thromboembolism Following Fractures of the Hip

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Authors

ESEdwin W. SalzmanCross-Cutting Cardiology WHWilliam H. HarrisButler University RDRoman W. DeSanctisElectrophysiology

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Implication

May support warfarin prophylaxis in hip fracture patients; leaves open optimal modern regimens and bleeding trade-offs.

Key Points

To evaluate the efficacy and safety of prophylactic anticoagulation with warfarin in preventing venous thrombosis and pulmonary embolism in elderly patients with hip fractures.
Controlled study conducted in elderly patients undergoing operative treatment and immobilization for fractures of the hip.
Administered prophylactic anticoagulation therapy with warfarin to reduce the incidence of postoperative thromboembolic complications.
Assessed rates of venous thrombosis and fatal pulmonary embolism related to lower-extremity surgical trauma and prolonged immobilization.
Examined the protective value of prophylactic warfarin in mitigating major morbidity and mortality following hip fracture surgery.

Cite This Study

Salzman et al. (1966) studied this question.

synapsesocial.com/papers/6a814b2b9fceb4fbd5e3e42d https://doi.org/10.1056/nejm196607212750302

Topics

Pulmonary embolism

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Anticoagulation for Prevention of Thromboembolism Following Fractures of the Hip

Discussion

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Implication

Key Points

Cite This Study

Topics

Anticoagulation for Prevention of Thromboembolism Following Fractures of the Hip

Discussion

Member takes

Implication

Key Points

Cite This Study

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