Why the study?
Does pomegranate peel extract reduce systolic blood pressure and oxidative stress in female spontaneously hypertensive rats?
Population
Female spontaneously hypertensive rat (SHR) model, 4- or 28-wk-old
Comparison
Pomegranate peel extract for 30 days vs Filtered water
Design
Preclinical
Follow-up
30 days
Authors
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Does not support clinical use; leaves open whether antihypertensive effects translate beyond this rat model.
Does pomegranate peel extract reduce systolic blood pressure and oxidative stress in female spontaneously hypertensive rats?
Pomegranate peel extract attenuates hypertension and associated vascular remodeling in a rat model, potentially through reduction of coronary ACE activity and oxidative stress.
Santos et al. (2016) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: