What question did this study set out to answer?

To examine the ethical scope of researchers' obligations to protect, treat, and support human subjects during clinical studies in developing countries.

March 30, 2000New England Journal of Medicine

Investigators' Responsibilities for Human Subjects in Developing Countries

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Authors

MAMarcia AngellHarvard University

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Implication

Ethical commentary examines investigator obligations toward human subjects in developing nations, highlighting critical dilemmas regarding standard of care and protection.

Key Points

To examine the ethical scope of researchers' obligations to protect, treat, and support human subjects during clinical studies in developing countries.
Assessed ethical standards and research oversight in a longitudinal study investigating risk factors for heterosexual HIV-1 transmission.
Evaluated study design involving cohorts across 10 rural village clusters in Uganda, surveyed on five occasions at 10-month intervals.
Identified unresolved tensions regarding the level of medical intervention and treatment researchers are obligated to provide to infected or high-risk participants in resource-limited settings.
Highlighted ethical challenges in conducting purely observational assessments of preventable disease transmission when effective clinical interventions may exist globally.

Cite This Study

Marcia Angell (2000) studied this question.

synapsesocial.com/papers/6a814fd3da9cafc35e339dc5 https://doi.org/10.1056/nejm200003303421309

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Implication

Ethical commentary examines investigator obligations toward human subjects in developing nations, highlighting critical dilemmas regarding standard of care and protection.

Investigators' Responsibilities for Human Subjects in Developing Countries

Discussion

Member takes

Implication

Key Points

Cite This Study

Investigators' Responsibilities for Human Subjects in Developing Countries

Discussion

Member takes

Implication

Key Points

Cite This Study

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