Why the study?
Does genetic predisposition and obstetric complications affect brain volumes in schizophrenic probands and their relatives?
Does genetic predisposition and obstetric complications affect brain volumes in schizophrenic probands and their relatives?
Ventricular enlargement in schizophrenia is a marker for genetic liability, particularly in males, and susceptibility is exacerbated by obstetric complications in familial cases.
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Supports ventricular enlargement as genetic liability marker in schizophrenia, especially males; leaves open obstetric complication interactions.
McDonald et al. (2002) studied this question.
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