Why the study?
Does levosimendan improve right ventricular hemodynamics and pulmonary vascular resistance in patients with ARDS and septic shock?
Population
35 patients with acute respiratory distress syndrome (ARDS) in association with septic shock
Comparison
Levosimendan 0.2 microg/kg/min as a 24-hour… vs Placebo as a 24-hour infusion
Design
RCT, randomly allocated, placebo-controlled
Follow-up
24 hours
Authors
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May support levosimendan for acute RV unloading in ARDS/septic shock; extends hemodynamic data to this population.
Does levosimendan improve right ventricular hemodynamics and pulmonary vascular resistance in patients with ARDS and septic shock?
In patients with ARDS and septic shock, a 24-hour infusion of levosimendan improves right ventricular performance and reduces pulmonary vascular resistance.
Morelli et al. (2006) studied this question.
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