Population
Leukemic and preleukemic AKR/J mice
Design
Preclinical
Authors
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May inform retroviral leukemogenesis mechanisms in mice; leaves open human relevance and needs validation in other models.
Leukemogenic polytropic viruses in AKR/J mice arise via genetic recombination involving at least three endogenous viral sequences.
Thomas et al. (1982) studied this question.
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