Why the study?
Does calculating the GRACE score with high-sensitivity cardiac troponin or adding BNP improve mortality prediction compared to conventional troponin in patients with acute coronary syndrome?
Does calculating the GRACE score with high-sensitivity cardiac troponin or adding BNP improve mortality prediction compared to conventional troponin in patients with acute coronary syndrome?
The GRACE score remains highly accurate for predicting short- and long-term mortality in ACS patients in the era of high-sensitivity troponin, and the addition of hs-cTn or BNP does not significantly improve risk prediction.
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GRACE score accuracy unchanged with hs-cTn; supports continued use in ACS but leaves open need for prospective validation.
Meune et al. (2011) studied this question.
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