Population
Coronary arteries from cardiac allografts and young individuals without disease
Design
Cross-sectional
Follow-up
up to 27 months post grafting
Authors
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May precede graft vasculopathy; hypothesis-generating for pathogenesis and leaves open therapeutic targeting.
Over-expression of uPA and PAI-1 in coronary arteries early after cardiac transplantation precedes morphological evidence of graft vascular disease, suggesting a potential role in its pathogenesis.
Mona K. Garvin (1997) studied this question.
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