What is the Clinical Significance for Improving the Pain Severity in the Pediatric Treatment? A Systematic Review

AbstractBackground:Improvement in pain intensity in children is the most important indicator of treatment success.Purpose:This systematic literature review aims to investigate the scientific evidence regarding the clinical significance difference for pain severity in children.Methods:A systematic literature search was conducted using Pubmed, Science Direct, Medline, ProQuest, Cochrane, and WOS Reviews databases on 14.01.2021. Studies with the search keywords were identified and independently assessed by reviewers.Results:The search yielded 587 potentially relevant articles after the removal of duplicates. Of these, only seven articles met the inclusion criteria. All studies were original articles, two of which were a small sample a randomized controlled study. Different measurement methods were used and positive results in terms of pain severity with a treatment program. The clinical significance difference for pain severity was determined between 0.3 and 5.9.Discussion:For the clinical significance difference in demonstrating an improvement in the severity of pain in children, the values in the age ranges of the children should be accepted and used.