Why the study?
Does percutaneous left atrial appendage occlusion balance thrombosis and bleeding risks compared to anticoagulation in patients with ESKD and nonvalvular atrial fibrillation?
Does percutaneous left atrial appendage occlusion balance thrombosis and bleeding risks compared to anticoagulation in patients with ESKD and nonvalvular atrial fibrillation?
Percutaneous left atrial appendage occlusion is proposed as a potential alternative to anticoagulation for stroke prevention in patients with ESKD and nonvalvular atrial fibrillation to balance thrombosis and bleeding risks.
Anticoagulation to reduce thromboembolic stroke risk due to nonvalvular atrial fibrillation in ESKD is associated with increased bleeding. There is an existing debate in ESKD centers around the pros and cons of anticoagulation. We propose percutaneous left atrial appendage occlusion as a third alternative to balance thrombosis and bleeding risks in this high-risk population.
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A 2021 study studied this question.
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