Why the study?
Does naringenin-7-O-glucoside protect H9c2 cardiomyocytes from doxorubicin-induced toxicity?
Population
H9c2 cardiomyocytes
Comparison
Naringenin-7-O-glucoside plus doxorubicin vs Doxorubicin (DOX) alone
Design
Preclinical
Authors
Loading...
Naringenin-7-O-glucoside may protect cardiomyocytes from doxorubicin in vitro; hypothesis-generating and should not yet change practice.
Does naringenin-7-O-glucoside protect H9c2 cardiomyocytes from doxorubicin-induced toxicity?
Naringenin-7-O-glucoside protects H9c2 cardiomyocytes from doxorubicin-induced toxicity by stabilizing the cell membrane and reducing reactive oxygen species generation.
Xiuzhen Han (2012) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: