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August 4, 2011Journal of Cardiovascular Pharmacology and Therapeutics

Infarct Size Reduction in Patients With STEMI: Why We Can Do It!

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Population

Patients with ST elevation myocardial infarction (STEMI)

Design

Review

Authors

NMNathan MewtonCPChristophe PiotMOMichel Ovize

Discussion

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Overview

Pre-reflow cardioprotection may limit reperfusion injury in STEMI; leaves open prospective randomized validation.

Structured PICO

P
Population
Patients with ST elevation myocardial infarction (STEMI)
I
Intervention
Protective interventions applied immediately before reflow on top of reperfusion therapy
O
Outcome
Infarct sizesurrogate

This review highlights that lethal reperfusion injury can be prevented by protective interventions applied immediately before reflow, reducing infarct size in STEMI patients.

Cite This Study

Mewton et al. (2011) studied this question.

synapsesocial.com/papers/6a8166d3adfa6baaaee1d2cbhttps://doi.org/10.1177/1074248411412379
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