Why the study?
Does arithmetic stress and hand-grip testing increase blood pressure more in normotensive patients with hypercholesterolemia compared to normal cholesterolemic controls?
Population
37 normotensive subjects, comprising 15 patients with hypercholesterolemia and 22 normal cholesterolemic…
Comparison
Arithmetic stress and hand-grip tests vs Normal cholesterolemic controls undergoing the…
Design
Case-control
Authors
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Hypercholesterolemia is associated with exaggerated BP reactivity to stress; hypothesis-generating for mechanisms and prospective risk assessment.
Does arithmetic stress and hand-grip testing increase blood pressure more in normotensive patients with hypercholesterolemia compared to normal cholesterolemic controls?
Normotensive patients with hypercholesterolemia exhibit exaggerated blood pressure responses to mental stress and exercise, which may be mediated by increased intracellular calcium and altered nitric oxide/cyclic GMP signaling.
Minami et al. (1999) studied this question.
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