Key result
Pressor responses to mental stress correlated with 24-hour blood pressure variability (r=0.56), while responses to isometric handgrip correlated with left ventricular mass index (r=0.73).
Why the study?
Do pressor responses to laboratory stressors correlate with 24-hour blood pressure variability and left ventricular mass index in normotensive and hypertensive subjects?
Population
44 middle-aged subjects, including normotensive subjects, WHO stage I essential hypertension, and WHO stage…
Comparison
Laboratory stressor testing including a mental… vs Comparison across three groups: normotensive…
Design
Cross-sectional
Authors
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May aid hypertension phenotyping via stress testing; leaves open clinical utility pending prospective validation.
Cross-Sectional (n=44)
Do pressor responses to laboratory stressors correlate with 24-hour blood pressure variability and left ventricular mass index in normotensive and hypertensive subjects?
Effect estimate: r = 0.73
p-value: p=<0.001
Pressor responses to mental stress and isometric handgrip exercise can serve as clinical indicators for 24-hour blood pressure variability and left ventricular hypertrophy, respectively, in patients with essential hypertension.
Murakami et al. (1996) conducted a cross-sectional in Essential hypertension (n=44). Laboratory stressor testing (mental arithmetic, isometric handgrip, bicycle ergometer) vs. Normotensive subjects was evaluated on Correlation between pressor response to isometric handgrip exercise and left ventricular mass index (r = 0.73, p=<0.001). Pressor responses to mental stress correlated with 24-hour blood pressure variability (r=0.56), while responses to isometric handgrip correlated with left ventricular mass index (r=0.73).
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