Diltiazem and Akathisia

Brief Reports1 December 1983Diltiazem and AkathisiaMICHAEL B. JACOBS, M.D.MICHAEL B. JACOBS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-99-6-794 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptCalcium entry blockers or calcium antagonists are being used for a growing number of cardiovascular problems (1). Because diltiazem (Cardizem; Marion Laboratories, Kansas City, Missouri), a recent addition to this group, offers certain advantages over the other currently available calcium antagonists (nifedipine and verapamil), it can be expected to be prescribed with increasing frequency (2). We report a previously unreported adverse effect of diltiazem, akathisia.A 62-year-old man with several medical problems was admitted to the Stanford Medical Service on 13 January 1983. For the previous 15 years he had had poorly controlled hypertension, adult onset (type II) diabetes mellitus,...References1. STONE P, ANTMAN E, MULLER J, and BRAUNWALD E. Calcium channel blocking agents in the treatment of cardiovascular disorders: II: Hemodynamic effects and clinical applications. Ann Intern Med. 1980;93:886-904. LinkGoogle Scholar2. STRAUSS W, MCINTYRE K, PARISI A, and SHAPIRO W. Safety and efficacy of diltiazem hydrochloride for the treatment of stable angina pectoris: report of a cooperative clinical trial. Am J Cardiol. 1982;49:560-6. CrossrefMedlineGoogle Scholar3. MARSDEN C and JENNER P. The pathophysiology of extrapyramidal sideeffects of neuroleptic drugs. Psychol Med. 1980;10:55-72. CrossrefMedlineGoogle Scholar4. MUNETZ M and CORNES C. Akathisia, pseudoakathisia and tardive dyskinesia: clinical examples. Compr Psychiatry. 1982;23:345-52. CrossrefMedlineGoogle Scholar5. ANTMAN E, STONE P, MULLER J, and BRAUNWALD E. 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Biomedicine. 1978;29:306-8. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: MICHAEL B. 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BRINK, PHARM.D. 1 December 1983Volume 99, Issue 6Page: 794-795KeywordsCalciumDiabetes mellitusHypertensionMedical services ePublished: 1 December 2008 Issue Published: 1 December 1983 PDF downloadLoading ...