Torsades de Pointes and Nifedipine

Letters and Corrections1 July 1982Torsades de Pointes and NifedipineHOWARD A. GRAYSON, JOSEPH D. KENNEDYHOWARD A. GRAYSONSearch for more papers by this author, JOSEPH D. KENNEDYSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-97-1-144_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Among the causes of the ventricular arrhythmia "les torsades de pointes," recently reviewed by Smith and Gallagher (1), are the coronary vasodilators phenylamine and lidoflazine. Recently, a patient under our care developed torsades de pointes after the administration of a single dose of the coronary vasodilator, nifedipine (Procardia; Pfizer, Inc., New York, New York).A 74-year-old white woman with type II, diet-controlled, diabetes mellitus was admitted 12 April 1982 for unstable angina pectoris. She had been followed regularly in the medical clinic for chronic atrial fibrillation (without evidence of atrioventricular heart block) and congestive heart failure. Both...Reference1. SMITHGALLAGHER WJ. "Les torsades de pointes": an unusual ventricular arrhythmia. Ann Intern Med. 1980;93:578-84. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByNifedipineDrugs Used to Treat Hypertension, Heart Failure, and Angina PectorisNifedipineEvaluation of the Rabbit Purkinje Fibre Assay as an in vitro Tool for Assessing the Risk of Drug-Induced Torsades de Pointes in HumansDrug Interactions with CisapridePart IV: Class II, Class III, and Class IV Antiarrhythmic Drugs, Comparative Efficacy of Drugs, and Effect of Drugs on Mortality - A Review of Their Pharmaco kinetics, Efficacy, and Toxicity*Probleme bei der Behandlung mit KalziumantagonistenPlacebo-Controlled Trial of Once-A-Day Isradipine Monotherapy in Mild to Moderately Severe HypertensionSide Effects — Overdosage — Contraindications — Drug InteractionsPart IV: Class II, Class III, and Class IV Antiarrhythmic Drugs, Comparative Efficacy of Drugs, and Effect of Drugs on Mortality ? A Review of Their Pharmaco kinetics, Efficacy, and ToxicityNebenwirkungen — Überdosierung (Vergiftung) — Kontraindikationen — ArzneimittelinteraktionenTorsades de pointes associated with drugs and toxins: Recognition and managementCalcium channel blockers that prolong the QT intervalAnti-anginal and betaadrenoceptor blocking drugsNifedipine and Torsades de PointesHOWARD A. GRAYSON, JOSEPH D. KENNEDYTorsade de Pointes and NifedipineDENNIS M. KRIKLER, M.D., EDWARD ROWLAND, M.D. 1 July 1982Volume 97, Issue 1Page: 144-144KeywordsArrhythmiaAtrial fibrillationDiabetes mellitusHeart failurePatientsUnstable anginaVasodilators Issue Published: 1 July 1982 PDF DownloadLoading ...