September 27, 2016Journal of Neurotrauma

Three Dimensional Quantification of Microarchitecture and Vessel Regeneration by Synchrotron Radiation Microcomputed Tomography in a Rat Model of Spinal Cord Injury

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Population

Rat model of spinal cord injury

Design

Preclinical

Follow-up

28 days

Authors

YCYong CaoGuangzhou University of Chinese Medicine YZYuan ZhouZhejiang Chinese Medical University SNShuangfei NiFirst Affiliated Hospital of Zhengzhou University

Discussion

Member takes

Implication

Hypothesis-generating for microvascular repair after SCI; requires human studies before clinical translation.

Structured PICO

Population

Rat model of spinal cord injury

Intervention

Synchrotron radiation μCT (SRμCT) imaging

Outcome

3D temporal-spatial changes in microvasculature post-SCI (vascular volume fraction, vascular bifurcation density, vascular segment density, and vascular connectivity density)surrogate

SRμCT imaging reveals that spinal cord microvasculature undergoes significant 3D remodeling and endogenous revascularization during the post-injury repair process in a rat model.

Cite This Study

Cao et al. (2016) studied this question.

synapsesocial.com/papers/6a816e5a2bdcf510039cddc5 https://doi.org/10.1089/neu.2016.4697

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Three Dimensional Quantification of Microarchitecture and Vessel Regeneration by Synchrotron Radiation Microcomputed Tomography in a Rat Model of Spinal Cord Injury

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Three Dimensional Quantification of Microarchitecture and Vessel Regeneration by Synchrotron Radiation Microcomputed Tomography in a Rat Model of Spinal Cord Injury

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider