Why the study?
Does growth hormone treatment reduce body fat and improve metabolic parameters in severely obese prepubertal boys?
Population
7 prepubertal severely obese boys aged 10-12 years
Design
Cohort
Follow-up
6 months of treatment plus an additional 6 months of…
Authors
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May support GH for fat loss in obese boys; hypothesis-generating and should not change practice without RCTs.
Does growth hormone treatment reduce body fat and improve metabolic parameters in severely obese prepubertal boys?
Growth hormone treatment for 6 months in severely obese prepubertal boys reduces body fat, likely via stimulation of catecholamine-induced lipolysis, without negatively impacting glucose homeostasis.
KAMEL et al. (2000) studied this question.
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