The acute hemodynamic effects of intravenous verapamil in coronary artery disease. Assessment by equilibrium-gated radionuclide ventriculography.

46 patients with coronary artery disease, stratified by baseline ejection fraction (>35% or <35%).

Intravenous bolus of verapamil (0.1 mg/kg or 0.06-0.075 mg/kg) administered over 1-1.5 minutes or 2-2.5 minutes.

Baseline (pre-administration control values).

Acute hemodynamic effects including ejection fraction, left ventricular volumes, cardiac output equivalents, and peripheral vascular resistance measured by serial equilibrium-gated radionuclide ventriculography.surrogate