Why the study?
Does varying inspired O2 tension affect alveolar-arterial O2 tension difference in normal men and women?
Population
16 normal men and women selected equally from the age groups 20–29 and 50–59 years
Comparison
Varying inspired O2 tension to achieve mean… vs Different levels of inspired O2 tension
Design
Other
Authors
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A-aD widens with age yet narrows at high PaO2; leaves open whether these physiologic shifts alter clinical oxygenation targets in older adults.
Does varying inspired O2 tension affect alveolar-arterial O2 tension difference in normal men and women?
Alveolar-arterial oxygen tension difference is significantly greater in older individuals and decreases significantly when alveolar oxygen tension is raised to 653 mm Hg.
Cole et al. (1963) studied this question.
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