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Article1 July 1947NEPHROGENIC DIABETES INSIPIDUS: TRANSMITTED BY FEMALES AND APPEARING DURING INFANCY IN MALESROBERT H. WILLIAMS, M.D., COLE HENRY, M.D.ROBERT H. WILLIAMS, M.D.Search for more papers by this author, COLE HENRY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-27-1-84 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThis paper reports an unusual type of diabetes insipidus. This entity has most likely existed before, but we have not found any evidence of its recognition as such. Before discussing the characteristics of the syndrome, a presentation of our studies is given, chiefly in the order that they were conducted.Patient C. H. A physician, aged 35, was recently admitted to the Boston City Hospital with pneumonia. His past health had been good, but he stated that he had had diabetes insipidus since infancy. In the course of treating the pneumonia with sulfadiazine it was observed that the concentration of...Bibliography1. HAMLANDIS GCEM: Comparison of pituitrin with antidiuretic substance found in human urine and placenta, Jr. Clin. Invest., 1942, xxi, 455. CrossrefGoogle Scholar2. GILMANGOODMAN ALS: The secretion of an antidiuretic hypophyseal hormone in response to the need for renal water conservation, Science, 1936, lxxxiv, 24. CrossrefGoogle Scholar3. TALBOTT JH: Personal communication. Google Scholar4. GOLDRINGCHASIS WH: Hypertension and hypertensive disease, 1944, The Commonwealth Fund, New York. Google Scholar5. WINER NJ: Renal function in diabetes insipidus, Arch. Int. Med., 1942, lxx, 61. CrossrefGoogle Scholar6. WARKANYMITCHELL JAG: Diabetes insipidus in children, Am. Jr. Dis. Child., 1939, lvii, 603. CrossrefGoogle Scholar7. TALBOTT JH: Diabetes insipidus, Nelson Loose-Leaf Medicine, 1941, 49. Google Scholar8. 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To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Boston, Massachusetts*Received for publication November 18, 1946.From the Thorndike Memorial Laboratory, Second and Fourth Medical Services (Harvard), Boston City Hospital, the Department of Medicine, Harvard Medical School, and the Mallory Institute of Pathology, Boston City Hospital, Boston, Massachusetts. 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