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March 10, 2009HypertensionOpen Access

Heightened Resting Neural Activity Predicts Exaggerated Stressor-Evoked Blood Pressure Reactivity

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Why the study?

Does heightened resting corticolimbic neural activity predict exaggerated stressor-evoked blood pressure reactivity in young adults?

Population

39 adults (19 men, 20 women) aged 20 to 37 years

Design

Cross-sectional

Authors

PGPeter J. GianarosPreventive CardiologyLSLei K. SheuUniversity of PittsburghICIsrael C. ChristieMichael E. DeBakey VA Medical Center

Discussion

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Implication

May link corticolimbic activity to BP reactivity; leaves open predictive value for cardiovascular outcomes.

Structured PICO

Does heightened resting corticolimbic neural activity predict exaggerated stressor-evoked blood pressure reactivity in young adults?

P
Population
39 adults (19 men, 20 women) aged 20 to 37 years
I
Intervention
Perfusion MRI to quantify resting regional cerebral blood flow (rCBF) prior to cognitive stressor tasks
O
Outcome
Task-induced rises in systolic and diastolic blood pressure (BP reactivity)surrogate

Heightened resting corticolimbic activity may serve as a neurobiological correlate for an individual's predisposition to exaggerated stressor-evoked blood pressure reactivity and associated cardiovascular risk.

Cite This Study

Gianaros et al. (2009) studied this question.

synapsesocial.com/papers/6a8175ae9fceb4fbd5e3f48ehttps://doi.org/10.1161/hypertensionaha.108.126227
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