January 1, 2017Circulation JournalOpen Access

Long-Term Outcomes of Non-ST-Elevation Myocardial Infarction Without Creatine Kinase Elevation　― The J-MINUET Study ―

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Population

3,283 consecutive patients with myocardial infarction

Comparison

Non-ST-elevation myocardial infarction without… vs ST-elevation myocardial infarction and…

Design

Cohort

Follow-up

up to 3 years

Authors

MIMasaharu IshiharaInterventional Cardiology KNKōichi NakaoKurume University YOYukio OzakiBoston University

Discussion

Member takes

Implication

NSTEMI patients warrant close long-term surveillance regardless of CK status; leaves open whether targeted strategies improve outcomes versus STEMI.

Structured PICO

Population

3,283 consecutive patients with myocardial infarction (2,262 STEMI, 563 NSTEMI with CK elevation, 458 NSTEMI without CK elevation)

Intervention

Non-ST-elevation myocardial infarction without creatine kinase elevation (NSTEMI-CK)

Comparator

ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction with creatine kinase elevation (NSTEMI+CK)

Outcome

Composite of all-cause death, non-fatal MI, non-fatal stroke, cardiac failure and urgent revascularization for unstable angina up to 3 yearscomposite

While patients with NSTEMI without CK elevation have better 30-day outcomes, their long-term outcomes (31 days to 3 years) are as poor as those with NSTEMI with CK elevation and significantly worse than those with STEMI.

Cite This Study

Ishihara et al. (2017) studied this question.

synapsesocial.com/papers/6a8175bf69a8c95c3f3cb51c https://doi.org/10.1253/circj.cj-17-0033

Topics

Heart failure HFrEF treatment

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Implication

NSTEMI patients warrant close long-term surveillance regardless of CK status; leaves open whether targeted strategies improve outcomes versus STEMI.

Long-Term Outcomes of Non-ST-Elevation Myocardial Infarction Without Creatine Kinase Elevation　― The J-MINUET Study ―

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Long-Term Outcomes of Non-ST-Elevation Myocardial Infarction Without Creatine Kinase Elevation　― The J-MINUET Study ―

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider

Long-Term Outcomes of Non-ST-Elevation Myocardial Infarction Without Creatine Kinase Elevation ― The J-MINUET Study ―

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Long-Term Outcomes of Non-ST-Elevation Myocardial Infarction Without Creatine Kinase Elevation ― The J-MINUET Study ―

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider

Long-Term Outcomes of Non-ST-Elevation Myocardial Infarction Without Creatine Kinase Elevation　― The J-MINUET Study ―

Long-Term Outcomes of Non-ST-Elevation Myocardial Infarction Without Creatine Kinase Elevation　― The J-MINUET Study ―