Why the study?
Does continuation of therapeutic warfarin reduce periprocedural stroke/TIA and bleeding compared to heparin bridging in patients undergoing atrial fibrillation ablation?
Does continuation of therapeutic warfarin reduce periprocedural stroke/TIA and bleeding compared to heparin bridging in patients undergoing atrial fibrillation ablation?
Performing atrial fibrillation ablation without interrupting therapeutic warfarin reduces thromboembolic risk without increasing bleeding compared to heparin bridging.
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May support uninterrupted warfarin in AF ablation; leaves open confirmation by randomized trials.
Santangeli et al. (2011) studied this question.
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