January 1, 1983Circulation
Beneficial effect of intravenous diltiazem in the acute management of paroxysmal supraventricular tachyarrhythmias.
Why the study?
Does intravenous diltiazem improve conversion to sinus rhythm or rate control in patients with paroxysmal supraventricular tachyarrhythmias?
Population
39 patients with paroxysmal supraventricular tachyarrhythmias, including 21 with organic heart disease and 7…
Design
Case_series
Follow-up
30 minutes
Authors
Discussion
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Implication
May support acute IV diltiazem use in PSVT; hypothesis-generating and requires randomized confirmation before practice change.
Structured PICO
Does intravenous diltiazem improve conversion to sinus rhythm or rate control in patients with paroxysmal supraventricular tachyarrhythmias?
P
Population
39 patients with paroxysmal supraventricular tachyarrhythmias (15 with supraventricular tachycardia, 12 with atrial fibrillation, and 12 with atrial flutter), including 21 with organic heart disease and 7 in heart failure.
I
Intervention
Diltiazem intravenous bolus of either 150 or 300 micrograms/kg over 2 minutes, with a second injection administered if the lower dose failed to reach the end point within 30 minutes.
O
Outcome
Conversion to sinus rhythm or slowing of the ventricular rate to 100 beats/min or less.surrogate
Intravenous diltiazem is highly effective and well-tolerated for the acute management of paroxysmal supraventricular tachyarrhythmias, achieving an 82% success rate for rhythm or rate control.
Cite This Study
Betriu et al. (1983) studied this question.