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August 16, 2026Open Access

A Convinient Synthesis of Thiazolo Pyrimido Benzothiazole Derivatives

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Authors

DKDigambar B. Kadam*

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Overview

Experimental synthetic study demonstrates a reaction route yielding thiazolo pyrimido benzothiazole derivatives, indicating efficient preparation of fused heterocyclic scaffolds.

Key Points

  • To establish a convenient and efficient synthetic route for producing novel thiazolo pyrimido benzothiazole derivative compounds.
  • Reacted 6-cyano-5-oxo-7-(methylthio)-5H-thiazolo[3,2-a]pyrimidine with substituted 2-aminobenzothiazoles in the presence of anhydrous potassium carbonate (K2CO3) base and N,N-dimethylformamide (DMF) solvent.
  • Characterized the synthesized products using mass spectrometry (MS), infrared (IR) spectroscopy, and proton nuclear magnetic resonance (1H NMR) spectroscopy.
  • Successfully synthesized novel 6-imino-5-oxo thiazolo[2,3-b]pyrimido[5,6-e]pyrimido[2,3-b] benzothiazole compounds.
  • Confirmed the exact chemical structures and atomic connectivity of all newly synthesized derivatives through IR, 1H NMR, and MS spectroscopic analyses.

Cite This Study

Digambar B. Kadam* (2026) studied this question.

synapsesocial.com/papers/6a81794cf2fb91fc834ac72ehttps://doi.org/10.5281/zenodo.21917442
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