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August 16, 2026VaccineOpen Access

Influenza vaccination uptake among people living with HIV in Melbourne, 2015–2025: a repeated cross-sectional study

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Authors

ARAmirpasha RafizadehMelbourne Sexual Health CentreDWDanushi WijekoonMelbourne Sexual Health CentreEAEi T. AungSt Vincent's Health

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Implication

Repeated cross-sectional study reveals suboptimal influenza vaccination uptake and pandemic-related declines in people living with HIV, highlighting gaps in immunisation tracking.

Key Points

  • To assess temporal trends in influenza vaccination coverage among people living with HIV and investigate reasons for non-vaccination.
  • Conducted a repeated cross-sectional study analyzing 18,879 electronic records of people living with HIV at a sexual health center between 2015 and 2025 using segmented logistic regression.
  • Reviewed a random sample of 1,100 unvaccinated records (100 per year) to categorize reasons for non-vaccination and estimate adjusted uptake accounting for external vaccination.
  • On-site vaccination was 39.6% (7,474/18,879), rising from 40.4% in 2015 to 46.7% in 2019, dropping to 22.9% in 2021, and recovering to 40.1% in 2025.
  • Pre-pandemic uptake increased by 4.8% annually (95% CI: 2.3–7.4, p < 0.001), but pandemic onset reduced the odds of vaccination by 65.5% (95% CI: 60.9–69.7, p < 0.001).
  • Chart review revealed that 31.8% (350/1,100) received external vaccination and 13.5% (146/1,100) declined, adjusting total estimated vaccination uptake to 58.6% (11,058/18,879).

Cite This Study

Rafizadeh et al. (2026) studied this question.

synapsesocial.com/papers/6a81796af2fb91fc834ac884https://doi.org/10.1016/j.vaccine.2026.129038
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Also Consider

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