What question did this study set out to answer?

To optimize the extraction and chemical deacetylation process of fungal chitosan from Pleurotus ostreatus mycelium waste using response surface methodology.

August 16, 2026Next MaterialsOpen Access

Extraction and optimization of chitosan yield and deacetylation quality from mushroom mycelium waste

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Authors

KSKavirajaa Pandian Sambasevam AZAdrina Zulkifli SBSiti Nor Atika Baharin

Discussion

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Overview

Response surface methodology demonstrates optimized deacetylation and yield of fungal chitosan from mushroom mycelium waste, highlighting a sustainable biopolymer recovery route.

Key Points

To optimize the extraction and chemical deacetylation process of fungal chitosan from Pleurotus ostreatus mycelium waste using response surface methodology.
Applied a 17-run Box-Behnken Design to evaluate three process variables: sodium hydroxide concentration (30–50%), reaction time (2–4 h), and temperature (100–150 °C).
Characterized the extracted biopolymer using ATR-FTIR spectroscopy, thermogravimetric analysis (TGA), scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDX).
Quadratic models demonstrated high predictive accuracy for degree of deacetylation (DDA; R² = 0.9740) and chitosan yield (R² = 0.9974).
The highest DDA reached 80.36% at 50% NaOH, 2 h, and 125 °C, while maximum chitosan yield achieved 21.85% at 30% NaOH, 3 h, and 100 °C.
Thermogravimetric analysis indicated a primary decomposition stage between 200–350 °C with approximately 46% weight loss and a residual mass of ~43% at 600 °C.

Cite This Study

Sambasevam et al. (2026) studied this question.

synapsesocial.com/papers/6a817a80f2fb91fc834ae564 https://doi.org/10.1016/j.nxmate.2026.103160

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August 16, 2026Next MaterialsOpen Access

Extraction and optimization of chitosan yield and deacetylation quality from mushroom mycelium waste

View Full Paper

Ask AI

Bookmark

Authors

KSKavirajaa Pandian Sambasevam AZAdrina Zulkifli SBSiti Nor Atika Baharin

Discussion

Member takes

Overview

Response surface methodology demonstrates optimized deacetylation and yield of fungal chitosan from mushroom mycelium waste, highlighting a sustainable biopolymer recovery route.

Key Points

To optimize the extraction and chemical deacetylation process of fungal chitosan from Pleurotus ostreatus mycelium waste using response surface methodology.
Applied a 17-run Box-Behnken Design to evaluate three process variables: sodium hydroxide concentration (30–50%), reaction time (2–4 h), and temperature (100–150 °C).
Characterized the extracted biopolymer using ATR-FTIR spectroscopy, thermogravimetric analysis (TGA), scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDX).
Quadratic models demonstrated high predictive accuracy for degree of deacetylation (DDA; R² = 0.9740) and chitosan yield (R² = 0.9974).
The highest DDA reached 80.36% at 50% NaOH, 2 h, and 125 °C, while maximum chitosan yield achieved 21.85% at 30% NaOH, 3 h, and 100 °C.
Thermogravimetric analysis indicated a primary decomposition stage between 200–350 °C with approximately 46% weight loss and a residual mass of ~43% at 600 °C.

Cite This Study

Sambasevam et al. (2026) studied this question.

synapsesocial.com/papers/6a817a80f2fb91fc834ae564 https://doi.org/10.1016/j.nxmate.2026.103160

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