Why the study?
Does the PFA-100 system accurately detect the inhibitory effects of ADP receptor antagonists compared to whole blood aggregometry in vitro?
Population
In vitro blood samples from 38 subjects
Comparison
PFA-100 system to assess in vitro effects of… vs Whole blood electrical aggregometry
Design
Preclinical
Authors
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PFA-100 may miss ADP antagonist effects in animals; leaves open its clinical monitoring role versus aggregometry.
Does the PFA-100 system accurately detect the inhibitory effects of ADP receptor antagonists compared to whole blood aggregometry in vitro?
The PFA-100 system has limited usefulness for monitoring the effectiveness of ADP receptor antagonists compared to whole blood aggregometry.
Golański et al. (2004) studied this question.
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