Key result
Chronic kidney disease accelerates atherosclerosis and complicates the diagnosis and management of acute coronary syndromes, requiring a careful balance between ischemic and bleeding risks.
Chronic kidney disease acts as a coronary artery disease risk equivalent that accelerates atherosclerosis and complicates both the diagnosis and therapeutic management of acute coronary syndromes.
The major cause of death in patients with chronic kidney disease is represented by cardiovascular events. Atherosclerosis is usually initiated by the association of traditional and non-traditional risk factors, and the acute thrombotic complications are more frequent in subjects with reduced glomerular filtration rate. The diagnosis of acute coronary syndromes is challenging due to the increased values of cardiac necrosis enzymes correlated with reduced renal function.
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Moisi et al. (2019) conducted a review in Acute Coronary Syndromes in Chronic Kidney Disease. Management of acute coronary syndromes was evaluated. Chronic kidney disease accelerates atherosclerosis and complicates the diagnosis and management of acute coronary syndromes, requiring a careful balance between ischemic and bleeding risks.
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