Suspected Ticagrelor-Induced Bullous Fixed Drug Eruption

Figure 1. Chronological evolution of the suspected ticagrelor-induced cutaneous hypersensitivity syndrome a. Post-primary percutaneous intervention. Multiple tense bullous lesions appeared (within one hour) on the distal flexor aspect of the right forearm. b. Day 5. Some of the bullous lesions spontaneously ruptured with serous drainage. c. Day 7. Bullous lesions still persisting and re-appearing on ticagrelor therapy. Ticagrelor has been switched to clopidogrel and rivaroxaban. d. Day 14. Almost all lesions have ruptured and are healing by secondary intention on a modified antithrombotic regimen. e. Day 30. The lesions have all disappeared with post-inflammatory hyperpigmentation on the current regimen.