Why the study?
Does gene expression profiling accurately distinguish between benign and malignant adrenocortical tumors?
Population
85 patients with benign adrenocortical tumors (n=74) and adrenocortical carcinoma (n=11)
Comparison
Genomewide gene expression profiling and… vs Benign adrenocortical tumors
Design
Cross-sectional
Authors
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These genes may aid adrenocortical tumor classification; leaves open prospective validation before any clinical adoption.
Does gene expression profiling accurately distinguish between benign and malignant adrenocortical tumors?
Gene expression profiling identified several genes, including IL13RA2 and HTR2B, with high diagnostic accuracy for distinguishing adrenocortical carcinoma from benign tumors.
Gustavo Fernandez‐Ranvier (2008) studied this question.
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