Why the study?
Can gene expression profiling of chromosome 11q13 distinguish adrenocortical carcinoma from benign adrenocortical tumors?
Population
54 adrenocortical tumors (11 carcinoma and 43 benign)
Comparison
Gene expression profiling of chromosome 11q13 vs Benign adrenocortical tumors
Design
Case-control
Authors
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May aid differentiation of adrenocortical carcinoma; hypothesis-generating and requires prospective validation before clinical use.
Can gene expression profiling of chromosome 11q13 distinguish adrenocortical carcinoma from benign adrenocortical tumors?
Six genes on chromosome 11q13 are downregulated in adrenocortical carcinoma and may serve as diagnostic markers to distinguish it from benign adenomas.
Fernandez‐Ranvier et al. (2008) studied this question.
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