Key result
Statins show potential renoprotective effects across clinical trials, though robust confirmatory data remain limited.
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Evaluates the renal effects of statins in chronic kidney disease, highlighting conflicting evidence regarding their renoprotective benefits.
Numerous trials have shown that chronic kidney disease increases the risk of cardiovascular disease. Dyslipidemias have been shown to accelerate progression of kidney disease. Statins have assumed a pivotal role in management of hyperlipidemia. However their effect on renal function is still not fully understood. Some clinical trials have shown some renoprotective effect of statins but there is still need for more data to clarify effects of statins on renal function.
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Mehra et al. (2011) conducted a review in Chronic kidney disease and dyslipidemia. Statins was evaluated on Renal function / renoprotective effect. Statins have shown some renoprotective effects in clinical trials, but no quantitative data were reported in this review and more data are needed to clarify their impact on renal function.
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