Lost in Markers? Time for phenomics and Phenomapping in Dilated Cardiomyopathy
Population
Patients with dilated cardiomyopathy (DCM) and inflammatory cardiomyopathy (CMi)
Design
Editorial
Authors
Discussion
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Implication
The editorial emphasizes the importance of comprehensive phenotyping of endomyocardial biopsies, including pro- and anti-inflammatory markers, to improve risk stratification and targeted therapies in dilated cardiomyopathy.
Structured PICO
P
Population
Patients with dilated cardiomyopathy (DCM) and inflammatory cardiomyopathy (CMi)
The editorial emphasizes the importance of comprehensive phenotyping of endomyocardial biopsies, including pro- and anti-inflammatory markers, to improve risk stratification and targeted therapies in dilated cardiomyopathy.
Limitations
- CD163 is only one of the markers of M2 macrophages
- Absence of screening for cardiotropic viruses
- Only screened for M2 and not for M1 macrophages
Cite This Study
Linthout et al. (2017) studied this question.