Key result
Standardizing heart failure etiology definitions and improving global registry science could enhance public health surveillance and reduce the burden of noncommunicable diseases.
Why the study?
Heart failure is a final common pathway for diverse diseases, but substantial confusion exists regarding how to describe, study, and track these underlying etiologies.
Standardizing the definition and tracking of heart failure etiologies in global registries could improve population health and facilitate implementation research.
Warrants consideration of standardized HF etiologies in registries; leaves open surveillance and NCD benefits without prospective validation.
Heart failure (HF) is a well-described final common pathway for a broad range of diseases however substantial confusion exists regarding how to describe, study, and track these underlying etiologic conditions. We describe (1) the overlap in HF etiologies, comorbidities, and case definitions as currently used in HF registries led or managed by members of the global HF roundtable; (2) strategies to improve the quality of evidence on etiologies and modifiable risk factors of HF in registries; and (3) opportunities to use clinical HF registries as a platform for public health surveillance, implementation research, and randomized registry trials to reduce the global burden of noncommunicable diseases. Investment and collaboration among countries to improve the quality of evidence in global HF registries could contribute to achieving global health targets to reduce noncommunicable diseases and overall improvements in population health.
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Agarwal et al. (2024) conducted a review in Heart failure. Standardizing heart failure etiology definitions and improving global registry science could enhance public health surveillance and reduce the burden of noncommunicable diseases.
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