Clinical Characteristics and Outcome of Acute Heart Failure in Korea: Results from the Korean Acute Heart Failure Registry (KorAHF)
Key result
AHF hospitalizations in Korea show improved acute care but 1-year mortality remains poor at ~18%.
- n=5,625
Study Design
Type
Cohort (n=5,625)
Multicenter
Yes
Structured PICO
P
Population
5,625 consecutive subjects hospitalized for acute heart failure (AHF) in 10 tertiary university hospitals in Korea, mean age 68.5, 53.2% male.
C
Comparator
Historical cohort from a previous registry performed in Korea a decade ago
O
Outcome
In-hospital mortality and one-year follow-up mortalityhard clinical
In Korea, acute heart failure management has improved with lower in-hospital mortality and higher advanced therapy use, though long-term prognosis remains poor.
Limitations
- The study is a patient registry, not a clinical trial, so assessment, management, and follow-up regimens were not standardized and unmeasured variables may have influenced results.
- Only tertiary educational hospitals participated, which might not represent the general population of heart failure patients in Korea.
- Causes of post-discharge mortality and re-hospitalization were not validated.
- Laboratory tests and echocardiographic results were not centralized.
Authors
Discussion
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Implication
Improved acute HF care in Korea does not extend to long-term survival; leaves open need for post-discharge strategies.
Cite This Study
Lee et al. (2017) conducted a cohort in Acute heart failure (n=5,625). Standard care for acute heart failure was evaluated on In-hospital mortality. In patients hospitalized for acute heart failure in Korea, in-hospital mortality was 4.8%, and while acute clinical care improved over the last decade, long-term prognosis remains poor with a 1-year mortality of 18.2%.