Key result
Treatment with a pacemaker and three cycles of chemotherapy led to significant regression of a right atrial Burkitt lymphoma and restoration of atrioventricular conduction with no pacing burden.
Why the study?
Primary cardiac tumors are exceedingly rare with variable clinical manifestations, and primary cardiac lymphomas infrequently manifest as atrioventricular block.
Case Report (n=1)
Primary cardiac lymphomas can rarely manifest as complete heart block, which may be reversible with chemotherapy and tumor regression.
Rare cardiac lymphoma may cause reversible AV block; leaves open optimal management and incidence in larger cohorts.
Primary cardiac tumors are exceedingly rare with variable clinical manifestations. This case involves a patient presentation of symptomatic complete heart block and cardiac imaging revealing a right atrial mass invading the myocardium consistent with Burkitt lymphoma on histopathology. The patient received definitive bradytherapy with a pacemaker and chemotherapy for the primary cardiac lymphoma. After three cycles of chemotherapy, the right atrial mass regressed significantly with restoration of atrioventricular conduction and no pacing burden. Primary cardiac lymphomas infrequently manifest as atrioventricular block and this case highlights cardiac masses as a potential etiology when evaluating new conduction disturbances and bradyarrhythmias.
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Usry et al. (2020) conducted a case report in Primary cardiac lymphoma with complete heart block (n=1). Pacemaker and chemotherapy was evaluated on Regression of right atrial mass and restoration of atrioventricular conduction. Treatment with a pacemaker and three cycles of chemotherapy led to significant regression of a right atrial Burkitt lymphoma and restoration of atrioventricular conduction with no pacing burden.
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