Key result
Systemic chemotherapy achieves remission and reverses complete AV block in primary cardiac lymphoma.
Why the study?
Primary cardiac lymphoma with complete atrioventricular block is rare, and data on recovery following systemic chemotherapy are limited.
Case Report (n=1)
Systemic chemotherapy can induce complete remission and reverse complete atrioventricular block in patients with primary cardiac lymphoma.
Chemotherapy may reverse AV block in primary cardiac lymphoma; single case leaves open need for confirmatory studies.
We describe a rare case of primary cardiac lymphoma associated with complete atrioventricular block, with recovery following systemic chemotherapy. A 61 year-old woman was admitted because of a massive pericardial effusion and complete atrioventricular block. Echocardiography disclosed several polypoid masses in the right atrium. A diagnosis of primary cardiac lymphoma was made. After three cycles of chemotherapy, the patient achieved a complete remission, the ECG showed first-degree atrioventricular block, and echocardiography revealed disappearance of the right atrial masses. This is the first report of a patient recovering from primary cardiac lymphoma and complete atrioventricular block following systemic chemotherapy. We conclude that aggressive treatment of this malignancy can improve cardiac function and the patient's prognosis.
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Nakayama et al. (2008) conducted a case report in Primary cardiac lymphoma with complete atrioventricular block (n=1). Systemic chemotherapy was evaluated on Remission and reversal of atrioventricular block. Systemic chemotherapy led to complete remission and reversal of complete atrioventricular block to first-degree block in a patient with primary cardiac lymphoma.
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