Synapse
⌘+K
Synapse
PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
October 15, 2021Medicine & Science in Sports & Exercise

Fitness Level‐ and Sex-Related Differences in Macrovascular and Microvascular Responses during Reactive Hyperemia

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Mixed results exist regarding fitness- and sex-related differences in FMD, and little is known about microvascular differences in untrained versus chronically trained males and females.

Do fitness level and sex affect macrovascular and microvascular responses during reactive hyperemia?

Comparison

Chronically trained vs untrained individuals across male and female sexes

Design

Cross-sectional physiological study

Key result

Chronic training was associated with greater peak blood flow (P≤0.0001) and faster microvascular desaturation and reperfusion rates compared to untrained individuals, despite no difference in %FMD.

Discussion

Loading...

Member takes

Overview

Combined NIRS-VOT and hyperemia measures may detect fitness-related vascular differences missed by %FMD alone; leaves open clinical utility and causality.

Study Design

Type

Cross-Sectional (n=31)

Structured PICO

Do fitness level and sex affect macrovascular and microvascular responses during reactive hyperemia?

P
Population
31 chronically trained and untrained males and females evaluated for macrovascular and microvascular responses during reactive hyperemia.
E
Exposure
High aerobic fitness (chronically trained) and male sex
C
Comparator
Low aerobic fitness (untrained) and female sex
O
Outcome
Macrovascular (flow-mediated dilation, FMD) and microvascular (near-infrared spectroscopy-vascular occlusion test, NIRS-VOT) responses during reactive hyperemiasurrogate

Integrating NIRS-VOT and reactive hyperemia blood flow outcomes identifies fitness- and sex-related differences in vascular function that are not detected by %FMD alone.

Cite This Study

A 2021 study reported a cross-sectional. Chronic training vs. Untrained was evaluated on Flow-mediated dilation (%FMD). Chronic training was associated with greater peak blood flow (P≤0.0001) and faster microvascular desaturation and reperfusion rates compared to untrained individuals, despite no difference in %FMD.

synapsesocial.com/papers/6a81a2f928bb6950eb60f4edhttps://doi.org/10.1249/mss.0000000000002806
View Full Paper
Ask AI
Bookmark
Share